- Obstetricians & Gynecologists, Spartanburg - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Occupational Health Care Physicians & Surgeons, Spartanburg - Occupational Medicine
- Occupational Health Care Professionals, Spartanburg
- Occupational Medicine Doctors, Spartanburg - Physicians & Surgeons
- Occupational Therapy, Spartanburg - Occupational Health Specialists
- Off Road Vehicles, Spartanburg
- Off Road Vehicles Parts & Accessories, Spartanburg
- Office Buildings & Parks, Spartanburg
- Office Equipment & Supplies Manufacturers, Spartanburg
- Office Space on Rent, Spartanburg - Executive Suites, Meeting Rooms, Conference Rooms, Virtual Offices, etc
- Office Supplies, Equipment & Office Furniture Stores, Spartanburg
- Oil & Gas Additives & Supplies, Spartanburg
- Oil & Gas Companies, Spartanburg
- Oil & Petroleum Products, Spartanburg - Merchant, Wholesalers, etc
- Oil And Petroleum Products, Spartanburg
- Oil Change & Lubrication, Spartanburg - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Spartanburg - Oil Companies
- Oil Petroleum Wholesale, Spartanburg
- Oilfield Trucking, Spartanburg
- Oils & Greases, Spartanburg
- Old Age Homes Service, Spartanburg
- Oncologists, Spartanburg - Cancer Doctors, Physicians & Surgeons (Oncology)
- Ophthalmologists, Spartanburg - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Spartanburg
- Opticians, Spartanburg
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- Optometrists, Spartanburg - Eye Doctors, Physicians & Surgeons (Optometry)
- Oral Surgeon, Spartanburg - Dentists - Oral & Maxillofacial Surgeons
- Oriental Rugs, Spartanburg
- Ornamental Greenhouses, Spartanburg
- Ornamental Nursery, Spartanburg
- Ornamental Nursery Services, Spartanburg
- Orthodontist, Spartanburg - Teeth Straightening, Invisalign & Dental Braces
- Orthodox Churches, Spartanburg
- Orthopedic & Prosthetic Appliances & Shoes, Spartanburg - Orthopedic Shoes
- Orthopedic Shoes, Spartanburg
- Orthopedists, Spartanburg - Orthopedic Surgery Doctors, Physicians & Surgeons
- Orthotics and Prosthetics, Spartanburg
- Other Attorneys & Lawyers, Spartanburg
- Other Attorneys & Lawyers, Spartanburg
- Other Building Materials & Supplies, Spartanburg
- Other Industrial Contractors, Spartanburg
- Other Lawyers & Attorneys, Spartanburg
- Other Lodging, Spartanburg
- Other Specialties, Spartanburg - Doctors, Physicians & Surgeons
- Outdoor & Lawn & Garden Equipment Repair & Service, Spartanburg
- Outdoor Equipment & Accessories, Spartanburg
- Outdoor Furniture & Patio Furniture, Spartanburg - Garden Furniture Stores
- Outerwear Stores, Spartanburg - Jackets, Sunglasses, Hats, Caps, Coats, Gloves & More
- Outsourcing Services, Spartanburg
- Oxygen & Respiratory Equipment & Supplies, Spartanburg - Oxygen Concentrator, Tank, Machine, etc
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