- Education, Orangeburg
- Education & Information Services, Orangeburg
- Educational & School Supplies & Equipment, Orangeburg - Classroom & Teacher Supply Stores
- Educational Consultants, Orangeburg
- Educational Consultants, Orangeburg
- Educational Facilities, Orangeburg
- Educational Financing, Orangeburg
- Educational, Philanthropic & Research Foundations, Orangeburg
- Educators, Orangeburg
- Electric Companies, Orangeburg
- Electric Motor Repair & Service, Orangeburg
- Electric Motors & Generators , Orangeburg
- Electrical Control Systems & Materials, Orangeburg
- Electrical Supplies, Parts & Equipment, Orangeburg - Wholesale & Manufacturers
- Electricians, Orangeburg - Electrical Contractors
- Electronics Funds Transfer, Orangeburg
- Electronics Manufacturers, Orangeburg
- Electronics Repair & Maintenance , Orangeburg
- Electronics Stores, Orangeburg
- Elementary Schools, Orangeburg
- Emergency Rooms, Orangeburg - Urgent Care Centers
- Emergency Services, Orangeburg
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- Emergency Vehicle Accessories, Orangeburg
- Emergency Victim Services, Orangeburg
- Employment Agencies, Orangeburg - Staffing Agencies
- Employment And Labor Relations Attorneys & Lawyers, Orangeburg
- Engineer & Architect Services, Orangeburg - Engineering & Architecture Service
- Engineering Consultants, Orangeburg - Consulting Engineers
- ENT, Orangeburg - Ears Nose & Throat Doctors, Physicians & Surgeons
- Entertainers & Entertainment Groups, Orangeburg
- Entertainers & Groups, Orangeburg
- Entertainment & Recreation, Orangeburg
- Entertainment Agencies & Bureaus, Orangeburg
- Entertainment Services, Orangeburg
- Envelopes, Paper & Stationery, Orangeburg - Office Supplies
- Environmental Consultants, Orangeburg - Ecological Consulting
- Episcopal Churches, Orangeburg
- Estate And Property Attorneys & Lawyers, Orangeburg
- Estate And Property Attorneys & Lawyers, Orangeburg
- Estate And Property Lawyers & Attorneys, Orangeburg
- European Cuisine, Orangeburg
- Evangelists, Orangeburg
- Excavation Contractors, Orangeburg - Excavating - Excavator Companies
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