- Education, Gaffney
- Education & Information Services, Gaffney
- Educational & School Supplies & Equipment, Gaffney - Classroom & Teacher Supply Stores
- Educational Facilities, Gaffney
- Educational Financing, Gaffney
- Electric Companies, Gaffney
- Electric Motor Repair & Service, Gaffney
- Electric Motors & Generators , Gaffney
- Electrical Control Systems & Materials, Gaffney
- Electrical Engineer, Gaffney
- Electrical Supplies, Parts & Equipment, Gaffney - Wholesale & Manufacturers
- Electricians, Gaffney - Electrical Contractors
- Electronic, Communications & Electrical Engineers, Gaffney
- Electronics Manufacturers, Gaffney
- Electronics Repair & Maintenance , Gaffney
- Electronics Stores, Gaffney
- Elementary Schools, Gaffney
- Emergency Services, Gaffney
- Emergency Victim Services, Gaffney
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- Employment Agencies, Gaffney - Staffing Agencies
- Employment And Labor Relations Attorneys & Lawyers, Gaffney
- Employment Assistance, Gaffney
- Engine Parts & Equipment, Gaffney
- Engineer & Architect Services, Gaffney - Engineering & Architecture Service
- Engineering Consultants, Gaffney - Consulting Engineers
- Engines & Transportation Related Equipment, Gaffney
- Engravers Jewelry & Trophies, Gaffney
- ENT, Gaffney - Ears Nose & Throat Doctors, Physicians & Surgeons
- Entertainment & Recreation, Gaffney
- Entertainment Services, Gaffney
- Environmental Conservation & Ecological Services, Gaffney - Ecosystem Services
- Environmental Products, Gaffney
- Environmental Products & Services, Gaffney
- Environmental Services, Gaffney
- Episcopal Churches, Gaffney
- Equipment Installation Contractors, Gaffney
- European Cuisine, Gaffney
- Exporters, Gaffney
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