- Machinery, Supplies & Equipment - Business Production Related, Clemson
- Mailbox Rental Services, Clemson
- Mailing, Delivery & Courier Service, Clemson
- Management Consultants & Services, Clemson
- Manicurists & Pedicurists, Clemson
- Manufacturing, Clemson
- Marriage & Family Counselors, Clemson
- Massage Therapists & Professional, Clemson
- Massage Therapy, Clemson
- Meeting & Event Planning Services, Clemson - Conference Consultants
- Men's Clothing Stores, Clemson - Clothes & Accessories
- Mental Health Specialists, Clemson - Psychologist, Psychiatrist, Psychotherapist, etc
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- Metaphysical Churches, Clemson
- Methodist Church, Clemson
- Mexican Restaurants, Clemson
- Miscellaneous Government, Clemson
- Miscellaneous Manufacturing, Clemson
- Miscellaneous Professional, Clemson
- Mortgage Bankers & Correspondents, Clemson
- Mortgages & Loans, Clemson
- Motor Vehicle, Clemson
- Motor Vehicle Rental & Leasing, Clemson
- Moving & Storage Supplies & Equipment, Clemson
- Moving Truck Rental , Clemson
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