- Sandwich Shop Restaurants, Landrum
- Savings Banks, Landrum
- Scientific & Laboratory Equipment & Instruments, Landrum
- Secondary Schools, Landrum
- Security & Surveillance System & Equipment, Landrum
- Security Brokers & Dealers, Landrum
- Sewing & Yarn Stores & Supplies, Landrum
- Sewing Contractors, Landrum
- Shipping Service, Landrum
- Shoe Stores, Landrum - Mens, Womens & Kids Shoes
- Shopping & Shopping Services, Landrum
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- Smoked Meat Restaurants, Landrum
- Snacks & Desserts, Landrum
- Social Services & Welfare, Landrum
- Soup & Salad Restaurants, Landrum
- Southern Style Restaurants, Landrum
- Specialty Animal Services, Landrum
- Specialty Stores, Landrum
- Sporting Goods Stores, Landrum
- Steel Erection Contractors, Landrum - Steel Erectors
- Stocks & Bond Brokers, Landrum
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