- Labeling Equipment & Supplies, Irmo
- Labor And Employment Relations Attorneys & Lawyers, Irmo
- Labor And Employment Relations Lawyers & Attorneys, Irmo
- Laboratories Medical, Irmo
- Land Surveyor, Irmo - Land Surveying Services
- Landscape Contractors & Designers, Irmo
- Landscaping, Irmo
- Late Night Restaurants, Irmo
- Lawn & Garden Equipment & Supplies, Irmo
- Lawn & Garden Services, Irmo
- Lawn & Tree Service, Irmo
- Lawn Maintenance Services, Irmo
- Lawn Mowers & Power Equipment, Irmo
- Lawyers & Attorneys, Irmo
- Lead Testing, Detection & Removal - Commercial & Industrial, Irmo - Lead Paint
- Lead Testing, Detection & Removal - Residential, Irmo - Lead Paint
- Legal & Tax Services, Irmo
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- Legal Professionals, Irmo
- Libraries, Irmo
- Licensed Counselors, Irmo
- Life Insurance, Irmo
- Lighting Fixtures & Equipment, Irmo
- Liquor Stores, Irmo
- Loans Check Cashing, Irmo
- Loans Personal, Irmo
- Loans Title Services, Irmo
- Locks, Irmo
- Locksmiths, Irmo - Residence, Commercial, Safe & Auto Car Locksmith
- Locksmiths Equipment & Supplies, Irmo
- Lodging, Irmo
- Log Homes - Log Cabins Builders, Irmo - Building Contractors
- Long Haul Trucking Companies, Irmo
- Long Term Care Facility, Irmo
- Lutheran Church, Irmo
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